Accutane – Pharmas Online Tue, 02 Aug 2022 10:56:17 +0000 en-US hourly 1 Accutane – Pharmas Online 32 32 Fortress Biotech, Inc. (NASDAQ:FBIO) Stock purchased by National Asset Management Inc. Tue, 02 Aug 2022 08:55:19 +0000

National Asset Management Inc. increased its position in Fortress Biotech, Inc. (NASDAQ: FBIO – Get Rating) by 30.5% in the first quarter, according to the company in its latest Form 13F filing with the Securities & Exchange Commission. The company held 145,550 shares of the biopharmaceutical company after purchasing an additional 34,000 shares during the period. National Asset Management Inc.’s holdings in Fortress Biotech were worth $198,000 when it last filed with the Securities & Exchange Commission.

Other hedge funds have also recently increased or reduced their stakes in the company. ProShare Advisors LLC acquired a new stake in shares of Fortress Biotech during Q4 valued at approximately $41,000. Lazard Asset Management LLC acquired a new stake in shares of Fortress Biotech during Q4, valued at approximately $56,000. Arete Wealth Advisors LLC raised its position in Fortress Biotech shares by 460.5% during the 4th quarter. Arete Wealth Advisors LLC now owns 61,651 shares of the biopharmaceutical company valued at $102,000 after acquiring an additional 50,651 shares during the period. Strs Ohio increased its position in Fortress Biotech shares by 167.4% during the fourth quarter. Strs Ohio now owns 51,600 shares of the biopharmaceutical company valued at $129,000 after acquiring an additional 32,300 shares during the period. Finally, PVG Asset Management Corp acquired a new equity stake in Fortress Biotech during Q4 valued at approximately $248,000. Institutional investors and hedge funds hold 30.92% of the company’s shares.

Changes to analyst ratings

Several research analysts have recently published reports on FBIO stocks. B. Riley reduced his price target on Fortress Biotech from $8.00 to $6.00 and set a “buy” rating for the company in a research report on Thursday, July 14. Cantor Fitzgerald reiterated a “buy” rating and set a $6.00 price target on Fortress Biotech shares in a Friday, May 13 research report. Finally, upgraded Fortress Biotech from a “sell” rating to a “hold” rating in a Thursday, May 19 research report. One equity research analyst gave the stock a hold rating and five gave the company a buy rating. Based on data from, the stock currently has a consensus rating of “moderate buy” and an average target price of $10.50.

Fortress Biotech Price Performance

FBIO stock opened at $0.86 on Tuesday. The stock has a market capitalization of $92.80 million, a P/E ratio of -1.00 and a beta of 2.10. The company has a debt ratio of 0.46, a quick ratio of 3.15 and a current ratio of 3.31. Fortress Biotech, Inc. has a 1-year low of $0.77 and a 1-year high of $3.81. The company has a 50-day moving average price of $0.89 and a two-hundred-day moving average price of $1.26.

Fortress Biotech (NASDAQ:FBIO – Get Rating) last reported results on Thursday, May 12. The biopharmaceutical company reported ($0.18) EPS for the quarter, beating the consensus estimate of ($0.28) by $0.10. The company posted revenue of $23.93 million in the quarter, compared to $20.06 million expected by analysts. Fortress Biotech had a negative net margin of 88.31% and a negative return on equity of 32.56%. During the same period of the previous year, the company achieved EPS of ($0.11). As a group, sell-side analysts expect Fortress Biotech, Inc. to post year-to-date EPS of -0.79.

Fortress Biotech Company Profile

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Fortress Biotech, Inc., a biopharmaceutical company, develops and markets pharmaceutical and biotechnology products. The company markets dermatology products, such as Ximino capsules to treat only inflammatory lesions of moderate to severe non-nodular acne vulgaris; Targadox for severe acne; Exelderm cream for symptoms of ringworm and jock itch; Ceracade for dry skin; Luxamend for dressing and treating wounds; and Accutane capsules for severe recalcitrant nodular acne.

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Want to see what other hedge funds own FBIO? Visit for the latest 13F filings and insider trading for Fortress Biotech, Inc. (NASDAQ:FBIO – Get Rating).

Institutional ownership by quarter for Fortress Biotech (NASDAQ:FBIO)

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Readers talk about the issues of the day Sat, 30 Jul 2022 22:00:00 +0000

What is Quickly? This is where readers speak out on the issues of the day. Do you have a quote, a question or a quip? Quickly call 312-222-2426 or email

So you think the downstate abortion protesters looked “a bit like the insurgency to you.” You must need glasses because it was a peaceful protest. There were no weapons, there were no police officers injured, there were no broken doors or windows. These were people protesting the removal of their rights, not people protesting a lost election.

If the Indiana Legislature decides to go after the birth control ban, a reminder that women on the Accutane medication should be on birth control. Accutane is a medication for people with severe acne. Accutane may no longer be available if contraception is prohibited. This will cause serious mental harm to those trying to improve their skin. Male patients will also be affected as the drug will not be available. For many reasons, you cannot ban contraception.

If you can’t pay your bills, shouldn’t you be allowed to vote? I don’t think I agree with that in principle, but in one specific case, I do. Donald Trump is known for refusing to pay his bills, and how many times has he gone bankrupt (six, in fact) because he couldn’t or wouldn’t pay what he owed, preferring to stiffen up and sometimes ruin small and large businesses that he owed money? So I guess that means Donald is disenfranchised. It couldn’t happen to someone more deserving.

Indiana Republican lawmakers as well as conservative politicians across the country have gone out of their way to denigrate the teaching profession in recent years. They questioned teaching methods, censored teaching materials and threatened to fire teachers for teaching our true history. Remember that the truth will “harm” our children! Guess what? The chickens have returned to roost. Translated, the actions of conservative politicians came back to haunt them. The school is about to open. Indiana alone is short of 3,000 teachers and support staff. Incidentally, Indiana’s average teacher salary is ranked 38th in the country! Teachers say there are three main reasons for leaving the profession: harassment from conservative lawmakers and parents, unruly young people and low pay. I hope our state legislators will be willing to serve as substitute teachers when not in session!

Republicans refused to pass the burn pit bill for health care for veterans with cancer. Just as they refused to pass the military housing retrofit bill and embezzled millions of veterans for border wall funds. If you vote Republican, stop saying you support the troops. You don’t! You’re just waving your flag and being a hypocrite.

In the running for the award for worst senator in a fiercely competitive field, Ron Johnson of Wisconsin shouts “energy independence”, but then votes against efforts to make us independent of computer chips, which is just as important. China could cut us off at any time (over Taiwan, for example), and our economy would shut down. It is essential that we are able to manufacture a sufficient quantity of these electronic components ourselves. But Johnson thinks the bill to support their production here in the US is just “corporate welfare”. And besides, if the Democrats are for it, then he must be against it. If the chip lobbyists only treated Johnson like the NRA does, then you can be sure he would have voted differently.

Finally found a truthful comment from a Quickly reviewer. Such truthful comments are rare. The lady said that the last presidential election was the biggest electoral robbery in the history of our country. So the protest was called an insurrection.

During a speech in DC, Trump called our country “a cesspool of crime.” Did he know he was talking about him? This guy knows nothing of imposture and is totally out of touch with reality. Trump may become the most corrupt president to ever serve in the White House. Dysfunction is his middle name. Yet he claims to have an answer to reduce the crime rate. A good start would be for him to stay at the Mar-a-Lago golf course. Again, I don’t blame Trump for his brazen hypocrisy. I blame those who still choose to support him despite his corruption. It is a crime to pour money in silence. It is a crime to attempt to bribe. It is a crime to pressure an election official to change the results of an election. It’s a crime to support a Capitol riot. At some point, we have to assume that he will be held accountable. Until then, Trump will continue his tirade against societal norms. Why? Because he knows that a majority of the Republican Party, despite the evidence, is still willing to ignore his corruption. How sad!


Flaviviruses make you smell like a scent to attract bloodthirsty Aedes mosquitoes, and you might be able to take a cheap and safe drug to stop them. Fri, 29 Jul 2022 07:00:01 +0000

Mosquito nets in a pediatric intensive care unit. Wikimedia

Dengue, Zika and other mosquito-borne flaviviruses in the Aedes are a major public health issue, sickening hundreds of millions of people and killing tens of thousands each year. These arboviruses are expected to spread better and to more people geographically in the future in our warming climate. For millennia, people have recognized that during outbreaks of mosquito-borne diseases, patients with these diseases should be protected from further mosquito bites (e.g. with bed nets) while recovering to limit the spread. of these diseases to healthy people. The reason for this is partly that recovering patients might be less able to protect themselves from mosquito bites because of their symptoms, and partly because mosquitoes might be more attracted to people with mosquito-borne diseases. Such a strategy would be evolutionarily advantageous for mosquito-borne pathogens to maximize their transmission. There is evidence of increased attraction of people infected with mosquito-borne diseases to blood-seeking female mosquitoes, via manipulation of their host. For example, we know that Plasmodium parasites produce an isoprenoid precursor that increases the release of volatile mixtures from human red blood cells, making malaria-infected mice much more attractive to Anopheles vector mosquitoes. However, until now it was not known whether arboviruses, transmitted by Aedes mosquitoes would similarly manipulate their host to maximize disease transmission.

Graphical summary of the article by Zhang et al.

In a tour de force of a study, Hong Zhang, Yibin Zhu and their colleagues at Tsinghua University demonstrated that mice infected with flaviviruses were significantly more attractive to blood searchers. Aedes mosquitoes. Mosquitoes were allowed to choose to move to cages closer to healthy or infected mice in a three-cage olfactometer as well as in a two-cage olfactometer. Mosquito preference was related to volatiles emitted by hosts, as evidenced by elimination of preference by elimination of volatiles.

By analyzing how the antennae of female mosquitoes reacted to the volatiles of healthy and infected mice, the researchers found that the mosquitoes reacted significantly to acetophenone, decanal and styrene, but not to the other volatiles. Acetophenone attracted more mosquitoes when placed on healthy mice or on a human hand, compared to solvent alone. Using GC-MS, ten to one hundred times more acetophenone was released from Zika virus and dengue infection compared to healthy mice.

Volatiles collected from the armpits of dengue patients attracted significantly more mosquitoes than either simple solvent or volatiles collected from the armpits of healthy donors. Volatiles collected from the armpits of dengue patients also contained ten to one hundred times more acetophenone than volatiles collected from the armpits of healthy donors.

When skin bacteria from mice infected with Zika or dengue virus were eliminated, mosquito preference for infected mice was eliminated, but not when gut bacteria were eliminated, indicating that the release of acetophenone is bound to skin bacteria of mice. Acetophenone release was also reduced to a level similar to that of healthy mice when the flavivirus-infected mice’s skin bacteria were removed, but not when their gut bacteria were removed.

Mice infected with dengue and ZIKV had ten times more bacteria, with an increased relative abundance of Bacillus and Staphylococcus, but a reduced relative abundance of Lactobacillus, compared to healthy mice. Bacillus bacteria produced large amounts of acetophenone when cultured on the skin of germ-free mice and elicited increased attraction of female mosquitoes looking for blood in the olfactometer at high enough concentrations.

Resistin-like molecule-α, an antimicrobial protein specifically expressed by epidermal keratinocytes and sebocytes, was expressed at significantly reduced levels in the skin of Zika virus and dengue infected mice, compared to healthy controls, on the basis of RNA-seq, qPCR and Western blot. This protein, along with its human analogue, RETN, significantly reduced the viability of the acetophenone-producing bacterium Bacillus, compared to other bacteria. Based on previous research, RELM-α can be induced by dietary derivatives of vitamin A, such as isotretinoin.

RELM-alpha production was restored to healthy levels in Zika virus and dengue infected mice that received isotretinoin by oral gavage, and the relative abundance of Bacillus bacteria on the skin of these mice n was also not significantly different from that of healthy mice. Moreover, blood-seeking female mosquitoes were not preferentially attracted to mice given isotretinoin, despite being infected with Zika virus and dengue fever. About half the number of mosquitoes were infected among the mosquitoes allowed to feed on mice infected with dengue virus and Zika virus when they received isotrenioine, when their Zika virus titers were not not significantly different.

In summary, the authors found that Zika and dengue viruses suppress the production of RELM-alpha, allowing Bacillus bacteria to proliferate, thereby increasing the production of acetophenone, which acts as a powerful lure for bloodthirsty mosquitoes. Additionally, this process can be impeded by the administration of isotretinoin, increased RELM-alpha, reduced Bacillus bacteria, and acetophenone production.

One of the strengths of this study is that it provides an in-depth analysis of this important topic, and it combines a large number of studies using a variety of techniques ranging from mosquito choice tests to electroantennograms to GS- MS, RNA-seq and microbiological studies in the quest to find the mechanism by which mosquitoes prefer infected mice and people. The study provides strong evidence that flaviviruses modify their host’s microbiome to increase the production of volatile compounds that attract mosquito vectors, ensuring their transmission to other hosts. This is similar to how Plasmodium parasites increase the release of volatile mixtures from human red blood cells to attract more Anopheles mosquitoes. There are also similar examples of insect-borne plant pathogens, such as when cucumber mosaic virus causes infected squash plants to produce a volatile mixture that attracts aphids despite the poor quality of the infected plant. . These results suggest that we have a whole other reason to protect people infected with flaviviruses from mosquito bites, because even all other things being equal, they will attract more mosquitoes.

Crystal structure of isotretionine molecule. Color Code: Dark Grey: Carbon; gray: Hydrogen, red: Oxygen. Image from Wikimedia

Another exciting part of this study was the demonstration that a dietary vitamin A derivative, isotretinoin, was able to reverse the attractiveness of infected animals, with only about half of the mosquitoes feeding on the host. infected. This is particularly exciting because it suggests that in addition to protecting recovering people from mosquitoes with bed nets and mosquito nets, we can counteract their increased attraction to mosquitoes by using a drug that is safe, inexpensive and easy to administer. Isotretinoin is already used to treat acne under the brand name Accutane, so it could be repurposed for this new indication, which would be much easier and faster to approve compared to a brand new drug. However, we must remember that this study was conducted primarily on mice, with the exception of taking volatiles from people’s armpits and testing compounds on their hands. A possible next step might be to conduct a randomized, double-blind study with dengue or Zika patients to see if administering isotretinoin orally would also increase RETN production in their skin, reduce the relative abundance of Bacillus and the production of acetophenone, and ultimately their attractiveness to female blood. look for mosquitoes. If the results remain comparable in human studies, we could halve the number of mosquitoes picking up Zika or dengue viruses from infected people, thus contributing significantly to the control of these flaviviruses.

Finally, the volatile responsible in the current study for the increased attractiveness of infected mice, acetophenone, is widely used in perfumes and perfumes, due to its floral and sweet scent to people. So the next time you travel to areas where dengue, Zika or other flaviviruses are endemic, or where Aedes populations (such as eastern North America), which will increase in the future, be sure to check that the perfume you wear does not contain acetophenone!

Are vaccines linked to birth defects? Thu, 28 Jul 2022 01:54:09 +0000

During pregnancy, it is natural to be concerned about the health of your baby. Eating well, exercising regularly and getting enough sleep can definitely benefit your baby. But what about vaccines? Can they protect you and your baby? Are there any risks?

Contrary to some of the rumors you may have read, vaccines are not linked to birth defects.

Here’s what you need to know about vaccines during pregnancy and how to protect yourself and your baby from potentially serious illnesses.

To date, there is no evidence that vaccination during pregnancy can cause birth defects or developmental problems for the baby.

In fact, vaccines during pregnancy have many benefits, including protecting you and your baby from serious complications associated with certain infections.

A 2017 major study analyzed more than 20 years of data reported to the National Vaccine Adverse Event Reporting System (VAERS) between 1990 and 2014. The researchers noted that there were few reports of birth defects. They also said there was no pattern in these reports indicating a condition caused by vaccines during pregnancy.

Most vaccines are safe during pregnancy. But some vaccines must be taken before you get pregnant or after you give birth.

Vaccines containing live virus are not recommended during pregnancy because there is a risk that live virus can cause infections in an unborn baby. However, even these vaccines have not been shown to cause birth defects.

The Centers for Disease Control and Prevention (CDC) recommends avoiding these vaccinations during pregnancy:

  • MMR
  • HPV
  • chickenpox (chickenpox)
  • tuberculosis
  • the flu shot, which is given by nasal spray (although the flu shot, given by injection, is safe and recommended during pregnancy)

If you plan to travel, try to get vaccinated before you become pregnant, if possible. These vaccines, often necessary for travel, are not recommended during pregnancy:

Discuss these vaccines with your doctor to determine if the benefits of the vaccine outweigh the risks. If you receive one of these vaccines and then find out that you are pregnant, tell your doctor immediately. You will probably need an extra dose if needed after giving birth.

Vaccinations before or during pregnancy are important for your health, as well as that of your baby.

With vaccination, you reduce the risk of certain infections that could lead to serious illness and potential pregnancy complications. Your baby also benefits from some of the antibodies created by vaccines in the first few months of life.

Even if you are fully immunized during pregnancy, your baby will still need to follow his childhood vaccination schedule and get fully vaccinated.

For example, newborns who contract the flu virus are at a higher risk of developing pneumonia. In addition, half of newborns who develop whooping cough (pertussis) are hospitalized with a serious illness.

You can help reduce these risks by getting vaccinated against these two viruses before or during pregnancy.

Ideally, you will be up to date on your vaccination schedules before getting pregnant. However, some vaccines are still needed at certain times during your pregnancy, such as those against influenza and whooping cough viruses.

There is no evidence linking the COVID-19 vaccine to birth defects. In fact, pregnancy is considered a risk factor to develop serious illness due to COVID-19.

Getting vaccinated against COVID-19 helps protect you from the disease and can help prevent serious symptoms if you develop them.

If you have not yet had the COVID-19 vaccine or are partially vaccinated, talk to a doctor or healthcare professional about the appropriate next steps based on your vaccination schedule.

During each pregnancy, the CDC recommends that you receive both your annual flu shot and whooping cough. The whooping cough vaccine is known as the Tdap vaccine, which protects against tetanus, diphtheria and whooping cough.

Immunization against pertussis and influenza during pregnancy not only protects you against the disease, but immunity can also extend into the first months of your baby’s life, when he is most vulnerable to these types of diseases. infections.

These benefits outweigh any possible – and unsubstantiated – claims for birth defects and developmental problems associated with whooping cough and flu vaccines. Always discuss vaccine information with a doctor or healthcare professional.

The CDC recommends the following vaccines during pregnancy:

Pertussis (whooping cough)

Pertussis is a serious disease and very contagious respiratory infection. Although this infection can be serious in anyone at any age, it can be fatal in infants.

Babies and young children do not start the series of pertussis vaccines until 2 months of age. So, getting vaccinated during pregnancy can help protect you and your baby from this potentially deadly infection.

Currently, the CDC recommends that all pregnant women receive a Tdap vaccine between week 27 and week 36 pregnancy, with earlier vaccinations within this period preferable. This ensures the best possible protection for your baby.

The whooping cough vaccine is considered safe. Although some people may experience side effects, these are generally mild and will not interfere with your daily activities. Some of them to understand side effects at the injection site, such as pain and swelling, fever, tiredness or upset stomach.


If you don’t already get an annual flu shot, now is a good time to start.

According to CDCpregnant people may be at higher risk for serious illnesses caused by the flu virus, possibly due to temporary changes in overall immune and organ function.

As with pertussis vaccination, timing is critical here to provide optimal protection against influenza.

The CDC recommends that pregnant women get the flu shot by the end of October to ensure the most adequate protection possible for mother and baby.


If you haven’t yet had your COVID-19 shot or need a booster, the CDC says it’s safe to get them while pregnant.

In fact, the The CDC recommends COVID-19 vaccination and booster injections during pregnancy. Their recommendations are in agreement with other professional medical organizations, such as:

Other vaccine recommendations

Other possible vaccines a doctor may recommend during pregnancy to understand:

  • hepatitis A, especially if you have a history of chronic liver disease
  • hepatitis B, if you have the infection, to prevent transmission to your baby during delivery
  • meningococcal vaccines before pregnancy, and possibly other bacterial and viral infections if you plan to travel abroad during pregnancy

Also, if you haven’t had an MMR vaccine yet, your doctor may recommend that you get vaccinated a month before trying to get pregnant.

This helps prevent possible birth defects, miscarriages or stillbirths due to rubella. Rubella is a serious and life-threatening form of viral infection.

Most vaccines are considered safe during pregnancy. There is no evidence to support a link between vaccinations and birth irregularities or developmental problems in a baby.

Although some vaccines can cause mild side effects, it is important to know that these can also occur outside of pregnancy.

Talk to a doctor or healthcare professional about any concerns you have about vaccines for you and your baby. They can make recommendations that will help ensure the best possible health for parent and baby.

The best ways to fight oily skin this summer Mon, 25 Jul 2022 22:42:00 +0000

Maybe you tried all the treatments mentioned above and nothing worked. If so, you may want to consider seeing your doctor or dermatologist so they can prescribe medications to treat your oily skin issues.

Board-certified dermatologist Ope Ofodile, MD, tells Cosmopolitan that there are some very effective medications that can help curb your body’s oil production and even shrink your sebaceous glands. But don’t get too excited just yet – isotretinoin (better known as Accutane), which is commonly prescribed to shrink sebaceous glands and reduce oil production, has some very serious side effects, you’ll want to you may be wondering if they outweigh the benefits. You can also ask your doctor if there are low-risk medications that will work for you, such as spironolactone, which works by targeting the hormone that triggers oil production.

If you don’t want to go for the strong stuff just yet, try a supplement. Speaking to Byrdie, board-certified dermatologist Marisa Garshick, MD, said you should look for a supplement that contains vitamins A and B3 and zinc. These compounds each work their own magic to take care of excess oil and acne. Byrdie recommends trying the MegaFood Skin, Nails, and Hair 2 supplement.

Acne bacteria thrive as skin oil disarms immune cells, study finds Fri, 22 Jul 2022 18:07:22 +0000

Cutibacterium acnes, a crusty Cheeto-shaped bug that lives on human skin, loves the oily pocket around hair follicles. No face is as oily as that of teenagers, flooded with hormones that grow hair, deepen voices and accelerate the production of sebum, a secretion that makes skin a moist, protective barrier.

Too little sebum means dry, scaly skin, like patches of eczema. Too much sebum means acne, the skin disease caused by C. acnes. Bumps, pimples and blackheads grow on most teenagers and, increasingly, on the faces of young adults, even in their 20s and 30s. And, in people with extra-oily skin, the body’s natural defenses seem unable to get rid of the bacteria.

A new study in Sciences Immunology gives clues as to why more than 45 million people suffer from acne, a disease that has been proven psychologically and socially devastating For the young. Directed by Robert ModlinProfessor Klein of Dermatology at UCLA, a team of researchers discovered overzealous and underperforming immune cells.


Macrophages are one of the first responders of our immune system. They rush to the site of a problem and are instructed to clean, remove dead cells, and get rid of pathogens and other unwanted treats. When it comes to acne-prone skin, macrophages are called upon to absorb extra oils – lipids – and kill bacteria that cause clogged pores and inflammation (that big red bump on a friend’s forehead). But something about the oil, a component of sebum called squalene, turns what should be a garbage truck into a reservoir for the growth of C. acnes bacteria. The Modlin lab studied the skin from the backs of six people — nearly 33,000 cells from day-old acne lesions and 29,000 cells from non-lesional skin — and simulated acne lesions in petri dishes to find a potential answer.

After analyzing the genetic sequencing, Tran Do, an MD-Ph.D. student and main author of the article, had the idea of ​​putting squalene directly in the box with the regular macrophages. What emerged were those mysterious “foamy” macrophages, called Trem2 macrophages, which Do later found mentioned in articles about other chronic fat-related diseases.


Trem2 macrophages clustered around fatty hair follicles, acting like nightmare guests. They got to work and stuffed themselves by gulping down as much oil as they could, but were “overly optimistic about the fat buffet,” Modlin said. Instead of defeating C. acnes, macrophages were stripped of their infection-fighting powers (although it’s still unclear how). One tactic: Squalene in the belly of a frothy macrophage finds oxygen radicals – molecules that can kill acne bacteria – and incorporates them into its oily stew, neutralizing the threat, leaving acne flourish.

“This acne bacteria is specialized to live there,” said Modlin, who is also a professor of microbiology, immunology and molecular genetics at UCLA. “It uses the lipids in that environment to grow, and it also worked with the host to avoid being killed.”

The research, published Friday, helps explain on a more granular level why benzoyl peroxide, a popular but irritating first-line treatment for acne, works. What Trem2 macrophages cannot accomplish, benzoyl peroxide can: overcome squalene’s oxygen radical-absorbing trick to kill acne bacteria. Knowing more about a particular pathway that leads to acne can open the door to other treatments or understanding why certain treatments, like the powerful drug Accutane, are so effective at curing acne, said Alvin Codadermatologist at the Scripps Clinic in La Jolla, California.

“You can have 10 different drugs with 10 different targets to treat one disease,” Coda said, because skin diseases are so complex, with inflammation being driven by multiple complex processes. The American Academy of Dermatology acne guidelines suggest that the best approach is to reduce sebum production, open pores and reduce inflammation. While research has affirmed since the late 19th century that C. acnes is involved in the formation of acne lesions, scientists are still studying exactly how and why acne occurs. Most agree that it is a multifactorial disease and that no one cause is to blame.

Understanding how lipids suppress the body’s immune response also has bigger implications, Modlin said. He found his way to research on leprosy acne (Hansen’s disease), his main area of ​​study, as the two diseases share a genetically similar bacterial infection. In some forms of leprosy, foamy macrophages can harbor hundreds of bacteria in each cell – an extreme version of what occurs in acne patients. “Your pimples go away in two or three days, so you end up defeating the bacteria,” he said. In severe leprosy, “the bacteria wins”.

But many other conditions, including certain forms of non-alcoholic fatty liver disease, obesity, Alzheimer’s disease, certain cancers, foamy cell tuberculosis and atherosclerosis, could be caused by foamy macrophages Trem2 “probably identical “.

In Alzheimer’s disease, there is an increase in Trem2-expressing macrophages – microglia – which scoop up lipids in the brain. In nonalcoholic steatohepatitis (fatty liver disease), researchers found more than Trem2 macrophages in the liver. These macrophages are also increased in many cancers, Harmeet Malhi, a consultant in the Mayo Clinic’s division of gastroenterology and hepatology, told STAT in an email. “Another interesting observation is that the age distribution of the three conditions does not overlap significantly, suggesting that these lipid-responsive macrophages may be involved in disease throughout life,” she says.

What scientists glean from inside pimples could eventually lead to the development of more targeted acne treatments and also help advance understanding of other chronic lipid-related conditions.

Acne Drug Market to Grow Exponentially by 2028 – Travel Adventure Cinema Thu, 21 Jul 2022 12:33:00 +0000

Global “Anti-Acne Drugs Market” report, history and forecast 2016-2028, breakdown data by companies, key regions, types and application. This report offers insightful insight into the drivers and restraints present in the market. The Anti-Acne Drugs Market data reports also provide a 5-year history and forecast for the industry and include data on global socio-economic data. Key stakeholders can consider the statistics, tables, and figures mentioned in this report for strategic planning that leads to organizational success. It sheds light on strategic production, revenue, and consumption trends for players to enhance sales and growth in the global Acne Drugs market.

This report examines the Acne Drugs market key factors influencing industry growth and explains how they contribute to industry growth. The report presents an unbiased perspective of the global acne medication market by comparing all key segments and markets. For the findings and analysis to be useful to industry players, the report assesses potential revenue generation strategies and recommends ideas for surviving in the industry. Therefore, by providing recommendations, this report hopes to help industry players in the right direction to compete and survive in the industry.

Get Sample PDF of Anti-Acne Drugs Market Report @

About Anti-Acne Drugs Market Report:-

This report contains Anti-Acne Drugs market size and forecast globally, including the following market insights:
Global Acne Drugs Market Revenue, 2017-2022, 2023-2028, (Million USD).
Global Anti-Acne Drugs Market Sales, 2017-2022, 2023-2028, (K Units).
Top five global anti-acne drug companies in 2021 (%).
The global Acne Drugs market was valued at Million in 2021 and is projected to reach Million USD by 2028, at a CAGR of % during the forecast period.

Top Key Companies of the Anti-Acne Drugs Market in 2022:

  • Ranbaxy Laboratories
  • Johnson & Johns
  • Go
  • Galder
  • GSK
  • valiant
  • Bayer
  • TV
  • F.Hoffmann-La Roche
  • La Roche-Posay

If you have any special requirements for this report, please let us know and we can provide you with a customized report.

Global Anti-Acne Drugs Market, by Type, 2017-2022, 2023-2028 (USD Million)

Global Anti-Acne Drugs Market Segment Percentages, by type2022 (%)

  • Accutane
  • Desquam-E
  • Cleocin T
  • Benzamycin
  • Topical erythromycin
  • Retina
  • minocin

Global Anti-Acne Drugs Market Segment Percentages, per app2022 (%)

  • Hospital pharmacies
  • Retail pharmacies
  • Online pharmacies

Global Anti-Acne Drugs Market, by Application, 2017-2022, 2023-2028 (USD Million)

Some of the key questions answered in this report:

  • What will be the market growth rate, growth momentum or market acceleration during the forecast period?
  • What are the key factors driving the Anti-Acne Drugs market?
  • What was the size of the emerging Anti-Acne Drugs market by value in 2022?
  • What will be the size of the emerging Anti-Acne Drugs market in 2028?
  • Which region is expected to hold the highest market share in the Anti-Acne Drugs market?
  • What trends, challenges and barriers will impact the development and sizing of the Global Anti-Acne Drugs market?
  • What are sales volume, revenue, and price analysis of top manufacturers of Acne Drugs market?

Get the Anti-Acne Drugs Market Report at Price $3250 for a single user license.

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1 Introduction to research and analysis reports
1.1 Acne Drugs Market Definition
1.2 Market Segments
1.2.1 Market by Type
1.2.2 Market by Application
1.3 Global Acne Drugs Market Overview
1.4 Features and benefits of this report
1.5 Methodology and sources of information
1.5.1 Research methodology
1.5.2 Research Process
1.5.3 Reference year
1.5.4 Report assumptions and caveats
2 Global Acne Drugs Market Size
2.1 Global Acne Drugs Market Size: 2021 VS 2028
2.2 Global Acne Drugs Revenue, Outlook and Forecast: 2017-2028
2.3 Global Acne Drugs Sales: 2017-2028
3 Business landscape
3.1 Acne Drugs Key Players in Global Market
3.2 Global Top Acne Treatment Drugs Companies by Revenue
3.3 Global Acne Drugs Revenue by Company
3.4 Global Acne Drugs Sales by Company
3.5 Global Anti Acne Drugs Price by Manufacturer (2017-2022)
3.6 Top 3 and Top 5 Acne Drugs Companies in Global Market, by Revenue in 2021
3.7 Global Acne Drugs Manufacturers Product Type
3.8 Anti Acne Drugs Tier 1, Tier 2 and Tier 3 Players in Global Market
3.8.1 List of Global Anti-Acne Drugs Tier 1 Companies
3.8.2 List of Global Anti Acne Drugs Tier 2 and Tier 3 Companies
4 curiosities per product
4.1 Overview
4.1.1 By Type – Global Acne Drugs Market Size Markets, 2021 & 2028
4.1.2 Accutane
4.1.3 Desquam-E
4.1.4 Cleocin T
4.1.5 Benzamycin
4.1.6 Topical Erythromycin
4.1.7 Retin-A
4.1.8 Minocin
4.2 By Type – Global Acne Drugs Revenue and Forecast
4.2.1 By Type – Global Acne Drugs Revenue, 2017 – 2022
4.2.2 By Type – Global Acne Drugs Revenue, 2023 – 2028
4.2.3 By Type – Global Acne Drugs Revenue Market Share, 2017 – 2028
4.3 By Type – Global Acne Drugs Sales and Forecast
4.3.1 By Type – Global Acne Medication Sales, 2017 – 2022
4.3.2 By Type – Global Acne Medication Sales, 2023 – 2028
4.3.3 By Type – Global Acne Drugs Sales Market Share, 2017 – 2028
4.4 By Type – Global Acne Drugs Price (Manufacturers’ Sale Price), 2017-2028
5 curiosities per app
5.1 Overview
5.1.1 By Application – Global Acne Drugs Market Size, 2021 & 2028
5.1.2 Hospital pharmacies
5.1.3 Retail pharmacies
5.1.4 Online pharmacies


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Lauren Chinn talks about her new “Acne” memoir Wed, 20 Jul 2022 19:00:46 +0000

Photo-Illustration: by The Cut; Photos: Brooke Nevin, Hachette Books

The coming-of-age memoir of Laura Chinn, Acne, begins by discovering his first zit, at the age of ten – typical kid stuff, right? Thing is, that’s pretty much where Chinn’s middle childhood ends. Soon after, her parents divorced and her brother was diagnosed with brain cancer, leaving her alone at home in Clearwater, Florida, while her mother and brother commuted for treatment.

Yet, as you might have guessed, her skin plays a central role in her life story. Chinn does Acne the title of her memoir to show how painful it was for her, though it should have paled in comparison to the other hardships her family faced. “My brother was blind and deaf and in a wheelchair, and I was always jealous of his fair skin,” she says. (At one point, Chinn accompanied his mother and brother on one such trip, to Tijuana, where he was prescribed unregulated Accutane for what became acne that masks his face.)

Having parents who weren’t at all interested in parenting and consumed by his brother’s illness made him grow up quickly: in his memoir, Chinn recounts his teenage years of drinking, smoking, having a best friend who broke her bathroom sink while having sex on it and trying to lose her own virginity. Additionally, she finds it hard to make fun of boys who grab her crotch at school, racist classmates (Chinn’s mom is white, her dad is black), and being around her brother for his eventual death. She drops out of high school but heads for an unlikely Hollywood ending in Los Angeles where she establishes a career in television (she’s the creator of Pop TV’s Florida Girlsand was also a writer and producer on Fox’s The mic and wrote for Fox’s Acquired rights).

Chinn says when she started talking about her formative years in writers’ rooms, “I was telling a story that I thought was pretty benign, and they were reacting so horrified. that was what being a teenager was like. I thought, like, witnessing gangbangs was part of everyone’s childhood. They also said she should write a book.

After battling acne for decades, what made you want to write a memoir about it? Didn’t you just want to get rid of it?

Part of it was because I had such a hard time talking about it. I was so ashamed of it, and even until a few months ago it was really hard for me to talk about it. And so there was some catharsis to write about it. So I started doing it, and then I started following the fact that acne had been that guideline my whole life. All these other things are going on, while I’m still dealing with this skin thing. It was also fun for me, the juxtaposition between my obsession with my skin and the horrors everyone was going through, like my brother with brain cancer.

You write about a childhood where you spent long periods of time without adult supervision. What do you think it taught you?

I don’t recommend it as a parenting technique, but I will say it has made me incredibly capable and not easily overwhelmed by life. When I was 20, my friends were scratching their cars and crying, and they didn’t know what to do. And I was like, “Well, you call a body shop, make an appointment, bring your car.” As I had taken care of myself for so long, it definitely made me a very capable adult.

You’re really honest in the book, about everything from being made fun of by a guy about your buttons to the lighting on set working as an actor to how lucky you were to avoid yourself injure or injure others while driving while intoxicated. What was the hardest part to write?

Drunk driving was certainly the most difficult; I still bear so much shame. Selfishness is deplorable. It’s hard to think of myself as someone who was capable of doing something so destructive, but I was. I wanted to write about it in hopes that someone else might learn from my actions, but it was hard to put the words in writing.

What was your parents’ reaction to reading the book?

It was difficult because I don’t think they knew how difficult it was for me. So I think there was a lot of emotion, and it’s one of those things where their cup was so full of taking care of my brother and their stress and horror of what was happening to my brother, and therefore to in many ways I think it was surprising for them to learn all that I was getting myself into and what my life was like without them. The extent of the danger, almost, how dangerous it was. My mom grew up in a completely different time when they used to run around the neighborhood and they didn’t do, you know, heroin. So I think it was quite alarming, the amount of danger a child can encounter if their parents are not present.

I was struck by your position that you weren’t going to use drugs, that you drew a hard line there.

It saved my life. It was a saving decision. It was really, really. I think there are young people who can take drugs, and they come out the other end, but I think young people who are going through trauma, who have been through trauma, sometimes drugs can take too much place, and I think I wouldn’t have survived. If I had started, I don’t think I would have stopped.

There are so many examples in the book where you write about downright racist people around you, seemingly unaware that your dad is black. How did you learn to assume your identity and defend yourself?

It’s funny. I found it all so hard to believe and so ridiculous that there was almost no evolution. It was like, immediately ridiculous to me and immediately I knew I was always going to tell whoever I was in front of that my dad was black, no matter how seemingly scary that person was or whatever point of view, and I don’t know why exactly? Because I was so young and so little, but I think because I had the gift of growing up in a house where everyone was a different color, I just had such knowledge at such a young age that’s a ridiculous point of view and doesn’t make any sense. And so yeah, it was almost like immediate, my reaction to that was almost immediate. People still don’t know I’m black, but I don’t live in a place where there are so many people who would talk racist in front of me. I don’t know if this is the place or if times have changed or if I just happen to be surrounded by more enlightened beings, but I don’t meet him anymore.

You dropped out of high school. Did you get a GED?

I dropped out of high school in second grade, then I went to a fake high school. It’s a high school by mail, so you send them money and they send you open book tests and then you get a high school diploma, but it’s not like it’s real. It’s kinda real, but it’s not real.

It’s the education you received when you started working as a screenwriter on television shows in Los Angeles. Do you suffer from impostor syndrome?

Huge impostor syndrome, until my husband completely changed my perspective, because I’d been in writers’ rooms with all these Ivy League educated people, and I was venting my insecurity to about it, and my husband said, ‘But Laura, so few of us went to school to write. And I was like, “Oh yeah,” because he went to Columbia for engineering. When I started asking people, they went for all these other reasons and I was like, They might know more about books or science or something. But many of us are self-taught even though we went to college. So that helped me a lot. But no, I had so much insecurity around not being educated.

How did you tell yourself to be, You belong in this room?

Literal claims that are exactly that. I listen and I still listen to a lot of affirmations. I used to see a woman who made me write affirmations every night before bed that are exactly that. I am Laura Chinn and I deserve to be here. I am Laura Chinn and I deserve good things. You’re just brainwashing yourself into believing you deserve it. And I recommend college because I think it took me a long time to get that sense of entitlement, but someone could get it in four years. They can get it easily in four years.

Back to your acne – you’ve tried to fix it in so many ways: Accutane, diet, and even the Scientologist-approved cleansing ritual. Can you tell us how you thought they would change your life?

Every time I was like, This is the answer. I’m so much harder on myself than anyone else, and when I have a flare-up I feel so heavy and there’s so much insecurity and self-hatred that comes to the surface. But when I see a breakout on someone else, I don’t notice it. And then if they report it, I’m like, I do not care. You are beautiful. But for me, one of the biggest challenges with this health issue is that I feel like I’m not allowed to have it. If you have another medical condition, you may have it and you may have a bandage or a cast on your leg or whatever. But in our society, we have decided that this health condition should be concealed and hidden and should be ashamed of it. And so it has always been very difficult for me. The shame aspect was always very, very difficult, and so with each new treatment, I was like, I no longer have to be ashamed of my health problem. It was like lying to yourself. I’m sure people do with all types of physical things they wish they could change, right? You think everything is going to go away and you are going to be confident. But then, honestly, I started doing some inside work and the confidence came more from within, and all the fantasies about how my skin was going to make me confident kind of went away, and I was like , Oh no, it’s all going to have to come from within, right?

People ‘viably fertile’ denied medication after failure Mon, 18 Jul 2022 14:45:02 +0000

In the weeks following the cancellation of Roe v. Wade, people are already feeling the negative effects – and not just people who need reproductive health care. Recently, for example, people with certain autoimmune diseases, including rheumatoid arthritis and lupus, have come forward to say their access to crucial drugs has been restricted as a direct result of Roe’s reversal. Do you suppose rheumatoid arthritis is related to reproductive rights? Probably not. But according to people with rheumatoid arthritis and lupus, the problem lies with a prescription drug they take to manage their condition: methotrexate. Drugs maybe, maybe, potentially, could be used to terminate ectopic pregnancies, and because of this, some people who need it and who are “viably fertile” (i.e. theoretically capable of becoming pregnant) report that their doctors refuse to continue to prescribe them, lest they therefore be exposed to legal repercussions. Many patients have gone online to say they don’t understand how it’s considered “pro-life” for their rheumatologists to deny them this life-saving drug.

Rheumatoid arthritis (RA) and lupus are inflammatory autoimmune diseases that cause a person’s immune system to attack their joints, but lupus also affects organs, skin, and muscles. Both come with painful side effects that methotrexate can help treat.

POPSUGAR contacted several rheumatoid arthritis physicians for comment, but received only one response from the hospital’s Special Surgery. In an email, Noelle Carnevale, associate director of public relations and media, said: “Hospitals are encouraged to direct inquiries regarding methotrexate to the American College of Rheumatology, which is currently working on a statement of position regarding this issue.”

On July 14, under a title titled “Access to Care – ACR and Roe v. Wade Decision,” the American College of Rheumatology website stated, “The ACR opposes any action that interferes with the practice of evidence-based medicine or impinges on the doctor-patient relationship. Pregnancy often complicates the care of women with rheumatic diseases and can threaten the life of the mother. Rheumatologists and other rheumatology professionals need to be able to provide the best evidence-based care and advice to all of their patients. At press time, the CAB had not responded to POPSUGAR’s email requesting additional comment.

Learn more about methotrexate and why some doctors refuse to prescribe it to “viably fertile” people here.

What is methotrexate?

Methotrexate is a prescription drug that is typically used as a treatment for autoimmune diseases such as rheumatoid arthritis, lupus, and certain cancers. It works to calm the immune system and reduce inflammation. There is some hope that it could one day be used for other purposes as well: a recent study, for example, found that methotrexate is “a suitable treatment option for patients who require immunosuppressive drugs for the COVID-19 pandemic”.

What is the connection between methotrexate and Roe v. Wade?

According to patients speaking on Twitter, the dispute over this beneficial drug arose shortly after the Supreme Court overturned Roe v. Wade. Some health professionals refuse to prescribe it to anyone who might be pregnant because it is considered an abortifacient (more on this). Although methotrexate is FDA-approved for treating joint inflammation (and 90% of rheumatoid arthritis patients use it at some point), some states classify it as an abortion-inducing drug – because it is sometimes used to treat ectopic pregnancies, and because it carries a risk of miscarriage for pregnant women. And it’s caused “confusion and caution in drug distribution,” Steven Schultz, director of state legislative affairs at the Arthritis Foundation, told Bloomberg Law.

Worthless: The process of treating an ectopic pregnancy is not considered an abortion. The American College of Obstetricians and Gynecologists website makes a clear distinction: “Although the indication and treatment of ectopic pregnancies are distinct from the indication and provision of induced abortion, they are all two of the essential and critical aspects of health care.”

What is an abortifacient? And what is the legality surrounding it?

An abortifacient is basically any drug that could be used to perform a medically induced abortion. In the United States, the FDA has approved a combination of two drugs named mifepristone and misoprostol (this is commonly known as the “abortion pill”) to terminate pregnancies up to 70 days of gestation. Currently, the Biden administration’s executive order protecting access to reproductive health services has promised to expand protections for access to medical abortion for people seeking an abortion or experiencing loss of pregnancy. However, Slate reported that even before Roe v. Wade, medical professionals and pharmacists in states with restrictive abortion laws, such as Texas, were hesitant to prescribe abortion drugs for fear of criminal prosecution. Now, that hesitation can affect drugs like methotrexate, which are abortifacients even though they’re not primarily used for medical abortions.

Will people also be denied other drugs?

Time will tell us. But it’s worth noting that methotrexate isn’t the only drug garnering increased attention following Roe’s reversal. Refinery29 recently reported that people who take Accutane – a drug that treats severe forms of acne – have expressed concerns about how the abortion bans many states are enacting might affect them, although for a different reason than people who need methotrexate to manage their RA or lupus symptoms. Accutane is well known to cause fetal abnormalities, so much so that the The FDA says patients must prevent pregnancy before, during, and one month after stopping the drug, which also requires patients to sign an iPledge in an effort to minimize fetal exposure. According to Refinery29, drug users are terrified that if their regular contraception fails and they become pregnant, they may have no choice but to carry the pregnancy to term.

Health care at all levels is under intense scrutiny now that the 50-year precedent set by Roe v. Wade has been removed. For example, in late June, South Carolina Governor Henry McMaster signed the Medical Ethics and Diversity Act into law, making it legal for medical practitioners to refuse “non-emergency” care if it conflicts with their personal beliefs – whether religious, moral or ethical. While this law affects everyone, it specifically allows for discrimination against the LGBTQ+ community, especially trans people seeking gender-affirming hormone therapy.

Allen Chaney, director of legal defense for the ACLU of South Carolina, told NPR that he expects the law to be challenged because discrimination based on sexual orientation and gender identity prohibited by federal law: not make it lawful.”

B. Riley cuts Fortress Biotech (NASDAQ:FBIO) price target to $6.00 Sat, 16 Jul 2022 05:55:38 +0000

Fortress Biotech (NASDAQ:FBIO – Get Appraisal) saw its price target lowered by stock analysts B. Riley from $8.00 to $6.00 in a note issued to investors on Thursday, reports The Fly. The company currently has a “buy” rating on shares of the biopharmaceutical company.

FBIO has been the subject of several other research reports. upgraded Fortress Biotech’s shares from a “sell” rating to a “hold” rating in a Thursday, May 19 research note. Roth Capital reissued a “buy” rating on Fortress Biotech shares in a research note on Tuesday, March 29. Finally, Cantor Fitzgerald reissued a “buy” rating and issued a $6.00 price target on Fortress Biotech shares in a research note on Friday, May 13. One investment analyst gave the stock a hold rating and five gave the company a buy rating. According to, Fortress Biotech has a consensus rating of “Moderate Buy” and an average price target of $10.50.

Fortress Biotech shares fall 0.9%

NASDAQ FBIO shares opened at $0.87 on Thursday. Fortress Biotech has a 12-month low of $0.77 and a 12-month high of $3.81. The stock has a market capitalization of $93.45 million, a PE ratio of -1.01 and a beta of 2.17. The company has a current ratio of 3.31, a quick ratio of 3.15 and a debt ratio of 0.46. The company has a 50-day moving average of $0.88 and a 200-day moving average of $1.39.

Fortress Biotech (NASDAQ:FBIO – Get Rating) last reported quarterly earnings data on Thursday, May 12. The biopharmaceutical company reported ($0.18) earnings per share (EPS) for the quarter, beating the consensus estimate of ($0.28) by $0.10. Fortress Biotech had a negative net margin of 88.31% and a negative return on equity of 32.56%. The company posted revenue of $23.93 million in the quarter, compared to $20.06 million expected by analysts. In the same quarter of the previous year, the company achieved EPS of ($0.11). As a group, sell-side analysts expect Fortress Biotech to post -0.77 EPS for the current fiscal year.

Fortress Biotech Institutional Trading

Several hedge funds have recently changed their positions in FBIO. National Asset Management Inc. increased its holdings of Fortress Biotech shares by 109.1% in the fourth quarter. National Asset Management Inc. now owns 111,550 shares of the biopharmaceutical company worth $279,000 after acquiring 58,200 additional shares in the last quarter. Strs Ohio increased its holdings of Fortress Biotech shares by 167.4% in Q4. Strs Ohio now owns 51,600 shares of the biopharmaceutical company worth $129,000 after acquiring 32,300 additional shares in the last quarter. PVG Asset Management Corp acquired a new position in shares of Fortress Biotech in Q4 worth approximately $248,000. Shikiar Asset Management Inc. increased its holdings of Fortress Biotech shares by 2.3% in Q4. Shikiar Asset Management Inc. now owns 710,500 shares of the biopharmaceutical company worth $1,776,000 after acquiring an additional 16,000 shares in the last quarter. Finally, GSA Capital Partners LLP acquired a new position in shares of Fortress Biotech in Q1 worth approximately $277,000. Hedge funds and other institutional investors hold 30.92% of the company’s shares.

About Fortress Biotech

(Get an assessment)

Fortress Biotech, Inc., a biopharmaceutical company, develops and markets pharmaceutical and biotechnology products. The company markets dermatology products, such as Ximino capsules to treat only inflammatory lesions of moderate to severe non-nodular acne vulgaris; Targadox for severe acne; Exelderm cream for symptoms of ringworm and jock itch; Ceracade for dry skin; Luxamend for dressing and treating wounds; and Accutane capsules for severe recalcitrant nodular acne.

See also

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