Acne Treatment – Pharmas Online http://pharmasonline.net/ Fri, 18 Jun 2021 11:14:31 +0000 en-US hourly 1 https://wordpress.org/?v=5.7.2 http://pharmasonline.net/wp-content/uploads/2021/05/pharmas-online-icon-150x150.png Acne Treatment – Pharmas Online http://pharmasonline.net/ 32 32 all you need to know http://pharmasonline.net/all-you-need-to-know/ http://pharmasonline.net/all-you-need-to-know/#respond Fri, 18 Jun 2021 08:30:00 +0000 http://pharmasonline.net/all-you-need-to-know/

Korean beauty tips: everything you need to know

Korean beauty hacks have always been a hype and that’s for all the right reasons and their outstanding results. Many big beauty brands have even introduced K-beauty products into their ranges.

In the summer our skin becomes prone to many skin conditions such as pigmentation and acne as the summer sun can be quite harsh and brutal on our skin. The warmer months make a tan inevitable and our obsession with DIY remedies begins to grow. Here we try to list some of the best K-beauty home remedies to take care of your skin this summer:

Yogurt face mask

We all pretty much know about the natural moisturizing properties of yogurt. The properties of yogurt that make it a staple in most Korean cuisines are its probiotic nature which makes it a preferred ingredient for skin care.

-Mix two tablespoons of yogurt with honey and one teaspoon of lemon juice

-Apply the mixture all over the skin and let sit for 15-20 minutes

– Wash and apply a soothing moisturizer

Lemon and strawberry face pack

Lemon is an antioxidant that naturally contains vitamin C. Vitamin C helps reduce skin damage and premature aging. Strawberry is a strong astringent and has anti-inflammatory properties which can protect our skin from UV rays and can also prove useful in the treatment of acne.

-Mix 2 drops of lemon juice with 3-4 mashed strawberries

-Add 2 tablespoons of yogurt to give it a thick consistency

-Apply the pack to your skin and let sit for 30 minutes

-Wash in lukewarm water

-Repeat the process twice a week

Rice water mist

Rice water mist

Rice water is one of the most popular ingredients used in many Korean beauty remedies and even their beauty products. Rice water is known for its lightening and anti-aging properties which help achieve clear and glowing skin.

– Soak the clean rice in water for about 30 minutes

-Pour the water into a spray bottle

-Add transparent aloe vera gel to the bottle

– Shake it and use it as a mist on the tanned areas of your skin

Green tea mist

Green tea is widely used as a key ingredient in Korean skin care. Women use green tea as a facial rinse to achieve clear glass skin. Green tea not only hydrates the skin, but also acts as a great toner for the skin.

-Boil green tea leaves

-Let cool

– Filter the green tea

-Pour the green tea water into a spray bottle

-Use it as a face mist 1-2 times a day

By: Chhavi Keswani


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Novan Announces Price of $ 40 Million Public Offering of http://pharmasonline.net/novan-announces-price-of-40-million-public-offering-of/ http://pharmasonline.net/novan-announces-price-of-40-million-public-offering-of/#respond Thu, 17 Jun 2021 13:00:00 +0000 http://pharmasonline.net/novan-announces-price-of-40-million-public-offering-of/

DURHAM, NC, June 17, 2021 (GLOBE NEWSWIRE) – Novan, Inc. (the “Company” or “Novan”) (NASDAQ: NOVN) today announced the price of the Company’s previously announced subscribed public offering (the “Offer”) of 3,636,364 common shares at a public offering price of $ 11.00 per share for gross proceeds of approximately $ 40 million, before deduction of sales rebates and commissions and other charges estimated bid payable by Novan. All of the common shares to be sold in the offer are being offered by Novan. The offer is expected to close on or around June 21, 2021, subject to customary closing conditions. In addition, Novan has granted the underwriter of the offering a 30-day option to purchase up to 545,454 shares of its common stock.

Cantor Fitzgerald & Co. acts as the sole accounting manager of the Offer. In addition, ROTH Capital Partners, LLC acted as financial advisor to the Company in connection with the Offer.

Novan intends to use the net proceeds of the Offering, together with existing cash, to fund the activities of the research and development program, including (i) the preparation and obtaining regulatory approval of its product candidate SB206 as a treatment for molluscum contagiosum, (ii) planning for the potential commercialization of SB206 and (iii) the pursuit of research and development activities mainly related to its product candidate SB204 as a treatment for acne vulgaris , as well as for general corporate purposes. .

The offering is being made in accordance with a pre-registration statement on Form S-3 (registration number 333-236583) filed with the Securities and Exchange Commission (the “SEC”) and declared effective April 10, 2020. A preliminary prospectus supplement relating to the offering has been filed with the SEC and a final prospectus supplement and the prospectus attached to this offering will be filed with the SEC. Securities may only be offered by means of a written prospectus, including a prospectus supplement, which forms part of the actual registration statement. When available, electronic copies of the Final Prospectus Supplement and the accompanying Base Prospectus relating to the Offer may be obtained from the SEC at http://www.sec.gov. Alternatively, copies of the final prospectus and the accompanying base prospectus relating to the Offer may be obtained, when available, from Cantor Fitzgerald & Co., Attn: Capital Markets, 499 Park Avenue, 4e Floor, New York, New York 10022 or by email at prospectus@cantor.com.

This press release does not constitute an offer to sell or the solicitation of an offer to buy such securities, and there will be no sale of such securities in any State or other jurisdiction in which such an offer, solicitation or sale would be illegal prior to registration or qualification under the securities laws of any such state or other jurisdiction.

About Novan

Novan, Inc. is a clinical development-stage biotechnology company focused on leveraging its proprietary nitric oxide (NO) -based technology platform, NITRICIL ™ to generate novel macromolecular chemical entities (NCEs) to treat multiple indications in dermatology, men’s and women’s health, infectious diseases and gastroenterological diseases with significant unmet needs. The Company’s lead product candidate is SB206, a topical antiviral gel, for the treatment of molluscum contagiosum. The Company believes that SB206 as a topical therapy applied at home by caregivers with rapid therapeutic benefit, if approved, would meet an important patient care need for the treatment of molluscum contagiosum.

Forward-looking statements

Any statements in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Such statements may be identified by words such as “believe “,” Expect, “” target “,” anticipate “,” can, “plan” “” potential “,” will “,” intends “and the like, and are based on beliefs and current expectations of the Company. These forward-looking statements include, without limitation, statements relating to the potential therapeutic value of the Company’s NITRICIL ™ platform technology, the Company’s pharmaceutical development of nitric oxide-releasing product candidates, statements regarding the Company’s expectations regarding the completion of the public offering, and statements regarding the intended use of the proceeds of the public offering. Forward-looking statements are subject to a number of risks and uncertainties that could cause actual results to differ materially from the Company’s expectations, including, but not limited to, the risks and uncertainties associated with the management processes. clinical development and regulatory approval, under market conditions and the satisfaction of customary closing conditions related to the proposed public offering, as well as other risks and uncertainties described in the Company’s annual report filed with the SEC on Form 10-K for the twelve months ended December 31, 2020, and in the Company’s subsequent filings with the SEC. These forward-looking statements speak only as of the date of this press release or of the announced presentation, as the case may be, and the Company disclaims any intention or obligation to update these forward-looking statements to reflect events or circumstances subsequent to the date of these declarations, unless required by law.

INVESTOR AND MEDIA CONTACT:
Jenene thomas
JTC Team, LLC
833-475-8247
NOVN@jtcir.com


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Caregivers Concern About Impact Of Severe Acne On Teens http://pharmasonline.net/caregivers-concern-about-impact-of-severe-acne-on-teens/ http://pharmasonline.net/caregivers-concern-about-impact-of-severe-acne-on-teens/#respond Wed, 16 Jun 2021 17:37:38 +0000 http://pharmasonline.net/caregivers-concern-about-impact-of-severe-acne-on-teens/

Over 90% of parents of teenagers with severe acne who took part in a recent survey sponsored by Sun Pharmaceuticals Industries in conjunction with the American Acne and Rosacea Society (AARS) said they were “very concerned” about the harmful impact of the skin disease on the physical, mental and social well-being of their teenager.1 They also expressed their concerns about the effects on their whole family and the lifelong physical scarring.

The catalyst for the online survey, which was conducted from October 29 to November 5, 2020, by Regina Corso Consulting of Sun Pharma, AARS and Hilary Baldwin, MD. “As dermatologists, we know [what our patients go through], but we never collectively looked at the impact it had on their parents, ”Baldwin said. Dermatology Time® and Contemporary Pediatrics®.

Over 90% of parents of teenagers with severe acne who took part in a recent survey sponsored by Sun Pharmaceuticals Industries in conjunction with the American Acne and Rosacea Society (AARS) said they were “very concerned” about the harmful impact of the skin disease on the physical, mental and social well-being of their teenager.1 They also expressed their concerns about the effects on their whole family and the lifelong physical scarring.

The catalyst for the online survey, which was conducted from October 29 to November 5, 2020, by Regina Corso Consulting of Sun Pharma, AARS and Hilary Baldwin, MD. “As dermatologists, we know [what our patients go through], but we never collectively looked at the impact it had on their parents, ”Baldwin said. Dermatology Time® and Contemporary Pediatrics®.

Hilary Baldwin, MD

“Children don’t live in a bubble and their parents take care of them every day and [going through it] right next to them, ”said Baldwin, medical director of the Acne Treatment and Research Center in Brooklyn, New York, and former president of AARS. “So with this survey, we wanted to make sure we better understand how parents feel about their teens with severe acne. “

The poll questions were informed by what Baldwin and his colleagues hear in their practices, such as teens who want to come home from school due to bullying, don’t want to have their picture taken, or quit the sports they love it because physical contact with other players will result in lumps on their chest or backs bursting and dripping blood on their uniforms. Wrestlers and swimmers told Baldwin they dropped out of the programs because of embarrassment when they took off their shirts. This has sometimes resulted in the postponement or loss of college scholarships.

“These are major changes,” she said. “Parents are hurting, some maybe as much as their children, and it’s time for people to recognize that. “

While there weren’t many surprises for Baldwin among survey respondents (n = 250), she was interested to see 55% of parents delaying dermatologist visits and starting more aggressive medications earlier. . The message must get out: Effective and early therapy is paramount for a positive outcome, Baldwin said. One result showed that 23% to 26% of parents allowed their teenagers with severe acne to use over-the-counter medications exclusively and 8% did not give them any medication.

“A lot of people think over-the-counter medications are good enough for severe acne. Once these products fail, parents are likely to turn to a dermatologist,” Baldwin said. “The biggest hurdle is? is not seeking care, but seeking appropriate care. Some parents struggle with the use of effective drugs. They want natural products, but these products just aren’t going to cut the mustard with lumpy or cystic acne.

She advised working with parents to allow their teens to use their favorite medications for “a little while,” but advised patients and their families that these products may not give optimal results. “Plan each step in advance,” she says. “Think about how these parents make decisions. Are they the hands? Helicopter parents? Did they drag their kids out kicking and screaming or did the teens instigate the visit to the office? Just keep in mind [that] you have to go fast. The longer it takes for people to get good aggressive therapy, the more likely they are to get physical and psychological scars.

Adherence is another issue, “more often than not non-compliance is based on forgetting,” noted Baldwin, however, sometimes there is a problem of control between parents who want their child to take medication and the child feeling under pressure and, in turn, not adhering.

In some cases, non-adherence may result from side effects of more potent drugs. “We have many new toys that are an improvement over the choices we had before,” said Baldwin. “New formulations for topical and oral medications as well as new active ingredients have improved tolerance. “

“At each visit, non-conforming behavior should be assessed, but it is important that providers and parents are not accusing. The script should recognize that teens forget, that they are tired, that they don’t want to get up early, that they don’t like the smell or the taste of the medicine, or maybe they have problems. unwanted effects, ”Baldwin said. . “Then discuss ways to improve this. “

Based on first-hand experience with his own teens who suffered from severe acne, Baldwin recommended combining taking the drug with some daily activity. “My kids probably wouldn’t be happy at all if they heard me share this, but I stuck the tube of medicine to the handle of the refrigerator door,” she said. “The first thing my kids did when they got home from school was walk to the refrigerator, and the rule was they didn’t open the refrigerator door until they applied their medicine. Place the medicine between the salt and pepper shakers on the table or near their toothbrush. Throw samples in their gym bags or jacket pockets, anything that improves their ability to remember to use it.

To keep adolescent patients and their parents on the same page, Baldwin recommended that, ideally, dermatologists allow 30 minutes to 1 hour for another acne visit. Talk about what acne is, why they have it, when it will get better or worse, what medications we generally have, what we are going to use for them, anticipated side effects and expectations of. improvement, ”she said.

She stressed the importance of tailoring the treatment plan to the patient’s preferences and lifestyle. “We need to learn a lot about our patients on that first visit, starting with how much acne bothers them. I ask on a scale of 1 to 10 – 1 being “What acne?” and 10 being, “Get that thing off my face now” just to find out what they’re going to do, “she said. “Someone who’s 10 will do whatever I ask him to do, I could throw him 6 drugs, and they’ll use all 6, while someone who’s 2 won’t use anything.”

Other relevant questions include whether the patient is a morning or evening, how hectic his mornings are, whether the equipment he wears for sports has headbands, chin straps, or objects that rub on his feet. shoulders, what time he comes home, and when they shower.

While it is vital to discuss the emotional and quality of life impact of this skin condition, Baldwin advised to postpone this discussion. “On the first visit, the teenager doesn’t know me from Adam and doesn’t trust me. This is not a time when he or she is likely to open up, ”she said.

On the second or third visit, she suggested an open statement such as: “This [severe acne] must make you very angry. She cautioned against pushing teenage patients to share their feelings if they don’t want to. “It is often helpful to ask the parent to leave the room, especially with adolescent male patients,” she said. “Try to schedule a time, perhaps via telehealth, to have a separate one-on-one with the parent to let them offload.”

Open ended questions about how patients deal with acne or if they are being bullied can facilitate the conversation. “Dermatologists don’t have a lot of time with each patient,” Baldwin said. “But we need to take the time to ask questions and listen to the responses of adolescent patients with severe acne or their parents.”

Baldwin also advised bringing in a trained therapist for referrals: “Sometimes the floodgates open and I don’t have the time or the expertise to close them,” she said. “Patients frequently refuse to see a therapist because of the stigma they perceive to be ‘crazy’. I explain to them that they are going through an extremely difficult time and that the benchmark is just to give them someone to talk to.

The survey found that 78% of parents surveyed felt they had in-depth conversations with their teens about the emotional side of acne. It was not his experience, according to Baldwin.

“I have twin daughters, who both had acne, both of whom needed isotretinoin, and what I learned was that it was really hard to know when to talk and what. say, “she said. “No matter what I said, it was the wrong thing and it resulted in an argument. This often happened at breakfast and they left for school on a bad note. I learned not to say anything, which was not easy. I learned to tell them about their acne in a quiet and peaceful time, maybe on the weekends when no one was mad at anyone.

“Another lesson was to tell them about their acne in a calm and quiet time, maybe on the weekend when no one was mad at anyone,” Baldwin said. “It also helped to have small snippets of conversation, to just leave a comment [such as], ‘Are you satisfied with your medications? Is there anything I can do to change them? ‘ I tried not to bring my teenage experience into the conversation because they didn’t appreciate me telling them how I was dealing with acne at their age. I ended up saying to them, “Talk to me if you want or I’ll help you find someone else to talk to.” You know I’m here and I’ll do whatever it takes. So leave him alone.

This article was originally published by Dermatology Times.

Disclosure

Baldwin is a paid consultant for Sun Pharma.

The references

1. Parents are very worried about the effects of severe acne on their teenage children, a new survey reports. Sun Pharmaceuticals in collaboration with the American Acne and Rosacea Society. Press release. Sun Pharma. April 7, 2021. Accessed May 13, 2021. https://www.sunpharmaderm.com/pdf/Sun_Pharma_Acne_Survey_Press_Release.pdf

2. Parents: Your teenager’s severe acne affects the whole family. Sun Pharma. Accessed May 11, 2021. https://www.sunpharmaderm.com/pdf/Sun_Pharma_Acne_Survey_Infographic.pdf


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The 25 Best Skin Care Products You Can Buy From Amazon http://pharmasonline.net/the-25-best-skin-care-products-you-can-buy-from-amazon/ http://pharmasonline.net/the-25-best-skin-care-products-you-can-buy-from-amazon/#respond Tue, 15 Jun 2021 21:06:14 +0000 http://pharmasonline.net/the-25-best-skin-care-products-you-can-buy-from-amazon/

CoffeeAndMilkGetty Images

Look, I’ll be honest. Every day, there is a war between my impatience and my laziness. Yes, I could walk to the pharmacy which is literally a few feet from my front door and buy some skin care products there. However, I could also sit on my bed, buy products online and wait for them to arrive. Of course, there are pros and cons to both. Then again, I could also just buy my beauty must-haves on Amazon, wait maybe a day instead of a week, and not have to travel at all.

You might think Amazon doesn’t have the best of the best when it comes to beauty, but oh, you’d be wrong. If you are looking to buy skin care online, Amazon is the jackpot. So whether you’re looking at a drugstore cleanser or that crazy, expensive moisturizer you saw a friend buy, Amazon is probably the place to look anyway. But who has time to scroll through the ages and ages to find the product you’re looking for? Below, find 25 of the best skin care products Amazon has to offer.

1

Clear UV Facial Sunscreen

It’s a model and actress favorite for a reason. It’s invisible, barely there, and it works. Like me in college.

2

2% BHA Skin Perfecting Liquid Exfoliant

Paula’s choice
amazon.com

$ 10.00

I mean, who still has time to deal with acne and wrinkles? This nifty liquid gently exfoliates pore-clogging annoyances so you can have a clear face in the summer.

3

Superfood Kale + Green Tea Face Wash

From youth to the people
amazon.com

$ 39.00

Just a quick explanation on how good this cleanser is: it’s so good, I’m really excited to wash my face at night just so I can use it.

4

Dew cream for the skin

You know you’ve been dying to try this moisturizer for the past couple of years, so just bite the bullet and hit buy. Believe me, this is actually amazing.

5

Spritz Mist and Glow Facial Spray Trio

Mario badescu
amazon.com

$ 21.00

You say you’re just gonna keep one and give the other two to your friends, but we both know that’s a lie. Collect them all and spray yourself every once in a while like you’re cold soda in an advertisement.

6

Daily Tonic with AHA Ready Steady Glow

REN Clean skin care
amazon.com

$ 38.00

Did being indoors for a full calendar year decrease your skin’s radiance factor? Yeah, the same. This skin tonic gently exfoliates for a brighter complexion that will make your ex regret breaking up with you on Zoom.

7

Luna Sleeping Night Oil

I think the biggest Disney myth that we’ve been fed on is that Sleeping Beauty woke up beautifully. But maybe it’s just because she smeared that nighttime oil on her face before she was cursed or whatever.

8

5% caffeine solution + EGCG

The ordinary
amazon.com

$ 12.00

Maybe it’s because I eat salt or drink wine, but my face in the morning is basically a giant puffy mess. This product is technically a caffeine infused contouring serum for puffy eyes, but I like to put it everywhere just in case.

9

Ultra Face Cream

This moisturizer has become a cult classic because it just works. Put on a little for oily skin and apply a thick layer for lizard skin (AKA, me). While you’re at it, you might as well just buy everything Kiehl’s makes, because none of it is bad.

ten

Bright screen SPF 40 PA +++

Super goup!
amazon.com

$ 36.00

You might think you hate wearing sunscreen, but that’s just because you haven’t tried this one yet. It’s almost invisible except for a thin glow that makes you feel like you’ve just received a facial.

11

All Purpose Skin Cream

Egyptian magic
amazon.com

This cream is like a balm-oil moisturizer that will heal even the most stubborn dry patches. It’s so thick and dreamy that I sometimes apply it on my elbows or cuticles just to give them a little relief.

12

Extra Strength Daily Peel Alpha Beta

Dr Dennis Gross
amazon.com

$ 150.28

In just four minutes, you can remove about a week of dirt and grime that has built up on your face from pollution, makeup, and whatever else you forgot to wash. Your face will go from dull to shiny so quickly.

13

Hydro Boost Hydrating Hyaluronic Acid Water Gel

For oily skin that stays away from super thick creams, this lightweight gel-textured moisturizer will keep you hydrated but won’t glow like a disco ball.

14

FAB Pharma BHA Spot Treatment Acne Gel

Beauty first aid
amazon.com

$ 26.00

Don’t let a pimple ruin your day. Put a drop of this treatment gel to soak up all the coarse things, unclog acne causing pores and look better overnight.

15

Deep cleaning strips for pores

Give your brain’s pleasure center a nice little reward when you take them off and see how many rude little guys have been forcibly removed from your face. It’s almost as satisfying as removing dating apps from your phone.

16

Squalane + Peptide Eye Contour Gel

Biosance
amazon.com

$ 54.00

Trick your boss that you got a full eight hours of sleep instead of putting off that super important presentation. Dark circles? None here!

17

ExfoliKate cleanser

Kate somerville
amazon.com

$ 40.00

The skin care world is obsessed with this product and you should be too. Everything from acne to unwanted skin texture is treated with this powerful cleanser.

18

Vitamin C Serum For Skin

buttah. by Dorion Renaud
amazon.com

$ 39.00

For dark spots and pesky hyperpigmentation, this serum uses vitamin C, collagen and heavy natural extracts of antioxidants to even out skin tone for the best skin ever.

19

Sébium refining cream for pores

Bioderm
amazon.com

$ 19.99

What if self-love didn’t include your pores? This cream alleviates their unsightly appearance and also acts as an excellent makeup base.

20

Indian healing clay

An old but a goodie, this deep cleansing mask pulls grime and grime out of your pores like a vacuum cleaner without the chore look. Add this clay powder to water or apple cider vinegar for a deep cleansing and watch your skin transform.

21

Regenerating Cleanser

Aunt harper
amazon.com

$ 84.00

Even for someone as leery of physical scrubs as I am, I have to admit that this product is excellent. It’s a little grainy without being aggressive, and my skin is so soft.

22

Care oil

Organic oil
amazon.com

$ 25.96

Beloved by all those who struggle with stretch mark scars, I have found that this oil is not praised enough for its effect on dry skin. Not only does it smother dry spots in the bud, but it also evens out my skin tone without breaking me down.

23

Retinol Correxion Deep Wrinkle Face Serum

Stop! Put down the Botox needle! Designed to treat deep wrinkles, not just those pretty crow’s feet, this serum uses retinol to tighten and lift aging skin so it becomes youthful and cheerful again.

24

Brightening Face Mask

Remember when the “face mask” was a skin care business, not a global pandemic? Pour a glass of white wine, soak in the bath, and soak up these skin-lightening ingredients for a fresher complexion.

25

Hydrating Face Cleanser

Who else hates that tight, crunchy feeling of the face after using a cleanser that’s far too strong? This lightweight, hydrating version of CeraVe leaves you so hydrated, you could probably take a few hours to notice that you forgot to apply a moisturizer.

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Study reports on the incidence in the United States, prevalence of granuloma annulare http://pharmasonline.net/study-reports-on-the-incidence-in-the-united-states-prevalence-of-granuloma-annulare/ http://pharmasonline.net/study-reports-on-the-incidence-in-the-united-states-prevalence-of-granuloma-annulare/#respond Mon, 14 Jun 2021 22:03:10 +0000 http://pharmasonline.net/study-reports-on-the-incidence-in-the-united-states-prevalence-of-granuloma-annulare/

A new cross-sectional study has detailed the prevalence of granuloma annulus in the United States, providing insight into its epidemiology and incidence.

Few large-scale population-based studies have explored the prevalence and incidence of the rare disease, and the burden of it has not been well established.

As such, a team led by John Barbieri, MD, MBA, of the Perelman School of Medicine, University of Pennsylvania, used the ICD-10 codes to assess patient data from the Optum Clinformatics database between January 1, 2017 and December 31, 2018.

“Optum Clinformatics Data Mart includes anonymized commercial claims data for approximately 18-20 million covered people in the United States each year,” they noted.

The study

The team collected demographic and clinical data from 11,608 patients with incident granuloma annulus as well as 17,862 patients with prevalent granuloma annulus. Of those with the incidental illness, 74.8% were female and the average age was 56.5 years.

Of those with prevalent granuloma annulus, 75.8% were female and the mean age was 56.6 years.

Thus, the overall annualized incidence was 0.04%, or 37.9 per 100,000 (95% CI, 36.9-38.9) person-years. The overall annualized prevalence was 0.06%, or 58.3 per 100,000 (95% CI, 57.1-59.5) person-years.

Barbieri and colleagues noted that the overall incidence of granuloma annulare was higher in women (female-to-male ratio, 2.8: 1; P<.001) and in those in the 5th decade of life.

The incidence among 50-59 year olds was 58.6 per 100,000 (95% CI, 55.2-62.0) person-years, compared with 34.6 per 100,000 (95% CI, 31, 9-37.2) person-years among 40-49 year olds. and 23.1 per 100,000 person-years (95% CI, 21.0-25.3) for those aged 30-39 (P <.001).

In addition, the incidence was higher in white patients (48.2 [95% CI, 46.8- 49.7]) than black patients (21.3 [95% CI, 18.8-23.9]; P <0.001).

Investigators also reported that the prevalence of granuloma annulare was also higher in women (female-to-male ratio, 3.0: 1; P<.001).

Similar to incident disease, the prevalence was highest in people in the fifth decade of life (91.5 per 100,000 [95% CI, 87.3-95.8] person-years) and white individuals (72.7 [95% CI, 70.9-74.4]).

“Within 6 months of their first diagnosis, 4822 patients (41.5%) filled a prescription for a topical corticosteroid, and 1087 patients (9.4%) received an intralesional injection,” they wrote. “Within 6 months of their first diagnosis, oral tetracycline class antibiotic prescriptions were filled by 820 patients (7.1%) and hydroxychloroquine prescriptions were filled by 268 patients (2, 3%). ”

Frequencies of treatment use were similar at month 12, investigators noted. Phototherapy, dapsone, systemic retinoids, and TNF inhibitors were rarely used as therapies.

Patients also rarely presented to the clinician other inflammatory skin disorders, such as acne (2.4%), psoriasis (1.2%), and atopic dermatitis (1.7%), within 3 months before or after the first diagnosis of granuloma annulare.

“These results provide important information regarding the basic epidemiology and the overall burden of granuloma annulare in the United States,” wrote Barbiere and colleagues. “Future studies are needed to better understand the association of granuloma annulus with quality of life and the most optimal treatment approaches for this condition.”

The study, “Incidence and prevalence of granuloma annulare in the United States, was published online in JAMA Dermatology.


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Salicylic Acid Vs Benzoyl Peroxide: Which Ingredient Is Best For Acne Removal? http://pharmasonline.net/salicylic-acid-vs-benzoyl-peroxide-which-ingredient-is-best-for-acne-removal/ http://pharmasonline.net/salicylic-acid-vs-benzoyl-peroxide-which-ingredient-is-best-for-acne-removal/#respond Mon, 14 Jun 2021 09:27:38 +0000 http://pharmasonline.net/salicylic-acid-vs-benzoyl-peroxide-which-ingredient-is-best-for-acne-removal/

Zits always show up at inconvenient times, right before a first date or in the morning of a big interview, so when they do show up you want to zap them ASAP. When it comes to over-the-counter acne treatments, benzoyl peroxide (BPO) and salicylic acid are usually the staples. They both tackle the dirt and bacteria that cause acne, but that’s where the similarities between the super ingredients end. They tackle different problems and work differently, but people often use them interchangeably. We spoke to two experts who explain the difference between these ingredients so you can determine what’s best for your condition and skin type.

What is Benzoyl Peroxide?

“BPO is a topical drug agent capable of killing the p.acne bacteria that can cause acne, ”says Dr. Chytra Anand, cosmetic dermatologist and founder, Kosmoderma Clinics and chief formulator, SkinQ. When applied, it breaks down and releases oxygen, which kills bacteria. Benzoyl peroxide kills bacteria (unlike antibiotics, which only slows their growth), so it has not been shown to contribute to bacterial resistance. “It reduces inflammation and works well on mild to moderate acne, including whiteheads,” she says. It’s best to treat inflammatory acne – the kind it’s red, hot, and painful to the touch, says Dr. Stuti Khare Shukla, cosmetic dermatologist and founder, Elements of Aesthetics Clinics.

It can cause dryness and irritation if you apply too much, so doctors suggest applying a very small amount only to the pimple or inflamed area. Plus, it also fits well in a prescription acne routine. “Benzoyl peroxide works best in combination with retinols and antibiotics like clindamycin,” says Dr. Anand. But it can cause flaking and peeling, so it’s best to hydrate well afterwards. Another word of warning? Keep sun protection nearby. “BPO can give you post-inflammatory pigmentation (especially if you have dry or sensitive skin), so it is advisable to use it only in your PM routine and to really apply sunscreen in the morning,” explains the Dr Shukla. applied only to very dry skin, as the absorption of BPO is increased if the skin is moist and can lead to erythema and irritation.

What is salicylic acid?

Unlike BPO, salicylic acid does not kill bacteria, so it can be used with different products for a complete treatment of your acne. It is a keratolytic and comedolytic beta-hydroxy acid, which means that it dissolves dead skin cells on the surface of the skin, then penetrates the pores, dissolves the oil and breaks up the debris on the skin. inside that can lead to acne. When you apply it to areas prone to whiteheads and blackheads (like the T-zone, cheeks, or nose), it can prevent acne from occurring in the first place. It is very oil soluble, so it can cut the fat on very oily skin to get inside each pore and really work.


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How eye drops can quickly make an angry pimple less red http://pharmasonline.net/how-eye-drops-can-quickly-make-an-angry-pimple-less-red/ http://pharmasonline.net/how-eye-drops-can-quickly-make-an-angry-pimple-less-red/#respond Sun, 13 Jun 2021 13:08:13 +0000 http://pharmasonline.net/how-eye-drops-can-quickly-make-an-angry-pimple-less-red/

Turns out this TikTok hack has legs (or, uh, eyes). According to a doctor certified in internal medicine and a skin care expert Zion Ko Lamm, MD, eye drops are an effective way to calm anger pimples – as long as you use the drops to “relieve the redness,” she explains in a duo video.

This is because the active ingredients in over-the-counter anti-redness formulas (usually tetrahydrozoline, naphazoline or brimonidine) are all vasoconstrictors, which means they can constrict blood vessels, which helps keep eyes clear. When applied to your skin, these vasoconstrictors can also help reduce redness and swelling (it has a soothing effect similar to that of green tea, for example, another known vasoconstrictor).

Although this is more of a quick fix. “It doesn’t treat your acne, but it’s a temporary hack!” Lamm said. You’ll want to use other spot treatment methods to get rid of the breakouts (salicylic acid, clay, etc.) because taming the redness doesn’t exactly target the root of the problem (clogged pores). Still, eye drops can work in a pinch, for example on the morning of an important event.

“[It] can even help with vascular-type dark circles, ”Lamm notes, as these types of shadows are exacerbated when blood vessels dilate. Again, this isn’t a long-term treatment (you’ll want to cure dark circles with these targeted treatments), but it works for temporary brightness.




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What are the benefits of using CBD oil? http://pharmasonline.net/what-are-the-benefits-of-using-cbd-oil/ http://pharmasonline.net/what-are-the-benefits-of-using-cbd-oil/#respond Sat, 12 Jun 2021 17:52:31 +0000 http://pharmasonline.net/what-are-the-benefits-of-using-cbd-oil/

As awareness of the medicinal value of marijuana spreads around the world, more and more states in the United States are allowing its use. As a result, a substance known as CBD oil is gaining popularity as a natural remedy for health issues such as anxiety, depression, and even cancer.

Plus, CBD oil and its benefits are all over the news these days, and rightly so. CBD, or cannabidiol, research continues to show the many ways this natural compound in cannabis can support our bodies and help in the treatment of several conditions.

It is quickly becoming a viable, all-natural alternative to conventional pharmaceuticals for a variety of conditions ranging from mild to extreme and even life-threatening. Many people assume that CBD oil only comes from marijuana and is still illegal and inaccessible to them due to decades of marijuana bans. However, this is not the case. Follow the link for More information.

Before we get into the particular benefits of this compound, it is important to remember that using CBD oil in any form is absolutely safe, as it is not addictive or addictive. to drugs. As a result, it is ideal for those looking to overcome addictions or refrain from using addictive substances. CBD oil has been documented to help with the following:

Chronic pain and inflammation

People who suffer from chronic pain associated with fibromyalgia have found relief by using CBD oil. It has also been found to relieve pain and protect the nervous system from degeneration. It is approved for the treatment of multiple sclerosis and cancer pain in Canada.

CBD has also been successful in reducing chronic inflammation and pain in some rats and mice, according to the authors of a report published in the Journal of Experimental Medicine. According to the researchers, the product can be used as a potential therapy for chronic pain.

Other than that, people with arthritis use it all the time because it has helped them manage their pain. If you have any doubts about the product, you can seek advice from your doctor. Many healthcare professionals recommend the use of this oil to their patients. Not only that, but people have confirmed that it is indeed helpful against arthritis.

Anxiety and depression

Many people struggle with depression on a daily basis. Anxiety is a milder physiological problem, but it can also strain a person’s body. In such cases, doctors recommend the use of antidepressants which sometimes work and sometimes not. They can also cause mild side effects.

Doctors typically warn people with chronic anxiety to avoid cannabis, as even trace amounts of THC can activate or worsen anxiety and paranoia.

However, researchers in a study published in the journal Neurotherapeutics in 2015 found that cannabidiol, which is a non-psychoactive compound, may really benefit patients with a few mental health issues like panic and general anxiety disorder. , post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD) and substance abuse disorders. Read more here.

These results, however, were concluded by laboratory experiments, clinical trials, and observational data, and there is currently no human research available. CBD has also been shown to relieve the tension and anxiety that comes with speaking in public. While there aren’t enough studies to conclude on the benefits, many people who have tried the oil have said that it has helped them in a number of ways.

Many healthcare professionals are also aware of the benefits, and that is why they do not encourage their patients against the product as long as they are careful about the dosage they are taking.

Migraine

What are the benefits of using CBD oil?

Neurological pain, such as migraines, has also been attributed to cannabidiol. Migraines are a common headache that can cause uncomfortable headaches ranging from mild to extreme. Although nasal sprays, pills, and pharmaceuticals have long been used to treat migraines, a growing body of evidence indicates that CBD oil can also be useful.

Due to its anti-inflammatory and analgesic properties, as well as its proven ability to relieve vomiting and relieve pain, it is believed to have the potential to help people with migraines.

Acne

CBD recently made headlines in the beauty industry, with hemp-derived skin care products hitting the shelves. It has been labeled “the last essential oil” in the industry. It is now a widely researched ingredient in topical skin care products.

Acne is one of the most common skin care problems that people seek remedies for. Acne is a very serious skin condition caused by various factors such as bacteria, genetics, and overproduction of sebum, so it’s probably best to see a dermatologist and determine the cause of your acne.

The overproduction of sebum associated with dead skin cells causes clogging of pores, one of the main causes of acne breakouts. CBD is believed to help regulate sebum development, reduce rashes, and possibly have an anti-inflammatory influence on the sebaceous glands. This makes it a useful product for preventing and treating symptoms of acne and inflammation.

There is positive anecdotal evidence of the impact of CBD on other skin conditions, in addition to helping treat symptoms of acne.

Conclusion

What are the benefits of using CBD oil?

These are just a few of the benefits of this life changing product. Studies are still ongoing, even though you are reading this article. Around the world, researchers are better understanding and adapting how CBD oil can help us live better, healthier, and more natural lives.


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Acne shouldn’t be taken at face value, when the problems can lie beyond the skin – Inklings News http://pharmasonline.net/acne-shouldnt-be-taken-at-face-value-when-the-problems-can-lie-beyond-the-skin-inklings-news/ http://pharmasonline.net/acne-shouldnt-be-taken-at-face-value-when-the-problems-can-lie-beyond-the-skin-inklings-news/#respond Sat, 12 Jun 2021 00:36:37 +0000 http://pharmasonline.net/acne-shouldnt-be-taken-at-face-value-when-the-problems-can-lie-beyond-the-skin-inklings-news/

It stands out in my face. It’s one of the first things that obsesses me every morning when I look at myself in the bathroom mirror. Even with my mask up, I’m still embarrassed and ashamed of what’s hiding underneath. I stay in bed some nights wondering what it takes to have clear skin: a magic pill? A wish granted by a genius? Despite its frequency, I can’t help but feel alone in my fight.

I’m talking about acne, of course, something all teenagers dread. The skin condition is simply known as “clogged pores” and is felt by almost everyone. 85% of all adolescents. As I said, it’s common, it’s not out of the ordinary, and it’s true that the stigma around it fell. Yet the stigma remains for those like me, whose condition is so much more than “clogged pores.” This is why, despite how caring and understanding others may be, they will never have a true understanding of the struggles that come with the fight against severe acne.

Even adults seem to miss the point. After explaining my skin journey online, a dermatologist sent me a message saying he did not agree with my dermatologist’s diagnosis and that his skin had improved over time, so mine too. . As humans, we tend to judge things beyond our control. It may be due to insecurity, fear, or arrogance, but most of our judgmental nature comes from confusion. Since not everyone has acne, the levels of understanding and knowledge around them differ from person to person. Empathy and comments lose their meaning because of this, which is why we need to better understand acne and its subtypes.

Acne can be caused by genetics, sweat, stress, facial products, and much more. It is rarely seen as something abnormal. After battling acne for almost six years now, I have realized that some causes of acne are beyond the skin. Because I am so young, my acne has always been treated thinking it was caused by oils or hormonal fluctuations. After seeing a new dermatologist, I learned that I had acne in adult women, caused by Hormonal imbalance.

Of course, hearing that my acne was more severe, as it might have something to do with my hormone levels, upset and embarrassed me. Although completely out of my control, I still blamed myself that my skin was horrible. I was even more embarrassed to admit it to others.

Even though it’s all acne, I knew it would be frustrating trying to explain why my acne is like this. After all, I was already on trial for the pimple spots on my face, would I be criticized even more if others knew I couldn’t control it?

My dermatologist told me that she couldn’t make my acne go away, but she could do it so that my acne was no longer a problem. As disappointing as it may sound to some, I was happy that she was honest about my skin and feeling more optimistic about the future. Knowing that this was something I had to learn to love, accept and live with forever helped me cope and take better care of my skin. It was a big step for me, and one that everyone should take: there are parts of us that are immutable and irreversible, but which are always part of what makes us unique.

With the disappearance of the stigma of acne, education must also be strengthened. Acne shouldn’t be seen as a ‘teenage problem’, it should be understood as something different for everyone. Teens need to feel informed and confident in explaining their skin to others. Although acne is not considered serious for others, its importance in my life is why I am so adamant and determined to raise awareness.


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What to know before your skin treatment http://pharmasonline.net/what-to-know-before-your-skin-treatment/ http://pharmasonline.net/what-to-know-before-your-skin-treatment/#respond Fri, 11 Jun 2021 17:06:48 +0000 http://pharmasonline.net/what-to-know-before-your-skin-treatment/

Warning: If you’ve tried all face lightening creams and exfoliating serums and still haven’t found an effective solution for your dark spots, uneven skin tone, or excess oil and shine, it may be. be time to reserve a glycolic. acidic skin. They are the secret to glowing skin– and unlike some of the ~ trending ~ skincare products today, they’re actually safe for most skin types. But if you’re still confused by all the exfoliation and unsure how a peel might fit into your routine, you’ve come to the right place.

Going forward, I asked two expert dermatologists and a master esthetician to explain everything you need to know about glycolic acid peels, including which skin types they’re best for, this what to expect in the days after your treatment, and more.

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What do glycolic acid peels do on your skin?

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First things first: glycolic acid is an alpha hydroxy acid (AHA) that works to loosen the bonds between skin cells in the outer layers of the skin. It’s basically a super ingredient – not only does glycolic acid gently exfoliate, but it helps lighten dark spots, even discoloration and smooth fine lines and wrinkles. Glycolic acid is also a boon for treating clogged pores and acne-prone skin, thanks to its ability to dive deep into the layers of the skin to dissolve excess oil and dead skin cells, explains the dermatologist. Tess Mauricio, MD.

TL; DR: Glycolic acid is a great exfoliant that helps you achieve softer, smoother and brighter skin without any irritation that accompanies mechanical exfoliators (i.e. those grainy scrubs or brushes). And given that it’s gentle enough for most skin types (more on this in a second), it makes sense that it has become such a popular ingredient for chemical peels.

Peels, by the way, are when a dermatologist or esthetician treats your skin with a concentrated amount of acid for a deeper exfoliation. That’s a higher and more controlled amount than anything you can buy over the counter, which means peels are great for anyone looking to take their exfoliation routine to the next level.

What skin types are best for glycolic acid peels?

According to the dermatologist and founder of Skin Wellness Dermatology Corey L. Hartman, MD, glycolic acid peels are best for normal, combination and oily skin. Remember: Glycolic Acid Peels help remove any buildup of sebum and wax in your pores that leads to acne, discoloration, and fine lines, so they’re especially suitable for oily skin.

Because glycolic is one of the most aggressive AHAs, people with dry or very sensitive skin may experience irritation, says Dr. Hartman. And since a peel makes your skin more sensitive to the sun, it’s absolutely essential — to all skin types — to wear sunscreen after your treatment.

One more thing to keep in mind: Dr Mauricio says those with active acne or sunburn should avoid glycolic acid peels, as open lesions can become irritated, resulting in tingling and inflammation. If you are unsure, there is no harm in booking a consultation with a pro to find out if you are the right candidate for a peel. Better safe than sorry, right?

How much does a glycolic acid peel cost?

The exact price of your glycolic acid peel will vary (it depends on where you are, which provider you choose, etc.), but you can usually expect to spend between $ 100 and $ 400. You’ll want to get your peel done with an experienced professional, so even if you find a good Groupon deal, it’s important to do your research and make sure you’re going to a certified dermatologist or licensed esthetician (it is your face, after all).

What happens during your appointment?

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Best thing about glycolic acid peels? Because you are working with a high dose of acid that only stays on the skin for a short time, it is a Great fast processing. According to Dr. Hartman, dermatologists typically use a concentration of 30 to 40 percent glycolic acid, and it stays on your skin for only two or three minutes.

Your practitioner will start by cleaning your skin and preparing it with a little alcohol to ensure that any oil or dirt is wiped off (this ensures that the skin is effectively penetrating your skin). Once you’re prepared and ready to go, a thin layer of acid is smoothed over your skin and left in place for the appropriate amount of time. After the withdrawal, you will be coated with SPF and sent on your way.

BTW: Despite the intensity of the word “peel”, it’s actually quite soft. You will feel tingling during application, but there is very little (if at all) burning, redness, or discomfort.

What does downtime look like?

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Immediately after a glycolic acid peel, your skin will usually be tight and look a little red. With some, between the second and third day, the skin after the peel may appear dry and may peel off and peel off (this is when the “peel” kicks in). Don’t worry, this feeling of dryness is just the completion of the exfoliation process that glycolic acid passes through your skin.

You can expect your skin to look and feel better after five to seven days, during which time you’ll want to gently treat your skin with soothing and moisturizing creams (like the choices below). Dr Mauricio tells his patients to avoid sun exposure (i.e. wear SPF and hat, ppl) for a week to avoid hyperpigmentation and to wear all-natural makeup during hair loss. 24 to 48 first hours. And the most important, do not use exfoliating products or devices until your skin is completely healed.

How often should you do a glycolic acid peel?

Well, it depends on the concentration of your peel, but in general, you can get treatment every two weeks for optimal results. Keep in mind, however, that too much of a good thing can turn into a bad thing. “Stronger glycolic peels with lower pH levels can only be done every six weeks, says master esthetician Karen fernandez. The general rule of thumb: don’t overdo it and work with your provider to find a frequency that works for your needs of the skin.

Can you do a glycolic acid peel at home?

Yes, and they’re a great option if you’re not looking to fork out the cash for in-office treatment or want something a little gentler. Peels at home are not as powerful as professional peels and they tend to have a lower concentration (think: 5 to 10 percent) of active glycolic acid. Dr. Mauricio says in-office peels can be more aggressive, penetrate deeper, and have more downtime, but they usually offer more dramatic improvement per treatment.

If you’re looking to do a home peel, start slowly (once a week at most) and then increase your frequency over time. Try not to layer acids, retinol, or benzoyl peroxide when using a home peel, otherwise you run the risk of irritation. These formulas are an excellent starting point:

Final thoughts

Want to try a glycolic acid peel yourself? Just remember that as with any new care product or treatment, you will want to present them carefully and slowly, whether at home or in an office with a dermis– and pair them with gentle cleansers and soothing moisturizers to offset potential dryness. I mean, IDK for you, but the idea of ​​getting softer, brighter skin after a few minutes in the dermis seems pretty ideal to me.

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